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NIST IR 8432 (Initial Public Draft)

Cybersecurity of Genomic Data

Date Published: March 3, 2023
Comments Due: April 3, 2023 (public comment period is CLOSED)
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Ronald Pulivarti (NIST), Natalia Martin (NIST), Fred Byers (NIST), Justin Wagner (NIST), Justin Zook (NIST), Samantha Maragh (NIST), Kevin Wilson (MITRE), Martin Wojtyniak (MITRE), Brett Kreider (MITRE), Ann-Marie France (MITRE), Sallie Edwards (MITRE), Tommy Morris (University of Alabama in Huntsville), Jared Shelton (University of Alabama in Huntsville), Scott Ross (HudsonAlpha), Phillip Whitlow (HudsonAlpha)


Genomic data has enabled the rapid growth of the U.S. bioeconomy and is valuable to the individual, industry, and government due to intrinsic properties that, in combination, make it different from other types of high-value data which possess only a subset of these properties. The characteristics of genomic data compared to other high value datasets raises some correspondingly unique cybersecurity and privacy challenges that are inadequately addressed with current policies, guidance, and technical controls.

This report describes current practices in risk management, cybersecurity, and privacy management for protecting genomic data, as well as the associated challenges and concerns. It identifies gaps in protection practices across the genomic data lifecycle and proposes solutions to address real-life use cases occurring at various stages of the genomic data lifecycle. This report also is intended to provide areas for regulatory/policy enactment or further research.

Submit Your Comments

The public comment period closes at 11:59 PM ET on April 3, 2023. Please email all draft comments to We encourage you to use this comment template when preparing and submitting your comments.


If you would like to help shape this project, consider joining the NCCoE Genomics Cybersecurity Community of Interest (COI). Email us at declaring your interest.

NOTE: A call for patent claims is included on page ii of this draft. For additional information, see the Information Technology Laboratory (ITL) Patent Policy – Inclusion of Patents in ITL Publications.



cyberbiosecurity; cybersecurity; genomic data; human genome; genomics; privacy
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