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high impact

Definitions:

  The loss of confidentiality, integrity, or availability that could be expected to have a severe or catastrophic adverse effect on organizational operations, organizational assets, individuals, other organizations, or the national security interests of the United States; (i.e., 1) causes a severe degradation in mission capability to an extent and duration that the organization is able to perform its primary functions, but the effectiveness of the functions is significantly reduced; 2) results in major damage to organizational assets; 3) results in major financial loss; or 4) results in severe or catastrophic harm to individuals involving loss of life or serious life-threatening injuries.)
Sources:
CNSSI 4009-2015 from FIPS 199 - Adapted

  The loss of confidentiality, integrity, or availability that could be expected to have a severe or catastrophic adverse effect on organizational operations, organizational assets, individuals, other organizations, or the national security interests of the United States; (i.e., 1) causes a severe degradation in mission capability to an extent and duration that the organization is able to perform its primary functions, but the effectiveness of the functions is significantly reduced; 2) results in major damage to organizational assets; 3) results in major financial loss; or 4) results in severe or catastrophic harm to individuals involving loss of life or serious life-threatening injuries).
Sources:
NISTIR 7622 under High Impact from FIPS 199